XTra™ DNA Kits for Automation

The XTra™ DNA Kits for Automation offer advanced solutions for automated purification of nucleic acids, tailored specifically for molecular biology applications. These kits are designed to streamline workflows, ensuring high-quality results with minimal manual intervention. They are ideal for purifying residual host cell DNA and viral nucleic acids from various samples, including bioprocess purification buffers, cell culture supernatants, and vaccine preparations.

These kits provide flexible and fully automated purification, allowing users to process up to 96 samples in a single run. The innovative design incorporates novel prefilled reagent cartridges, reducing setup time and eliminating the need for manual handling. Additionally, barcode reading enables comprehensive tracking of reagents throughout the purification process.

The principle behind XTra™ DNA Kits for Automation revolves around their compatibility with a diverse range of sample types encountered in bioprocesses, including cell-culture supernatants, fermentation broths, and fractions from vaccine purification. Whether isolating residual host cell DNA or viral nucleic acids, these kits leverage proven magnetic particle technology to deliver high-quality nucleic acids free from contaminants, proteins, and nucleases.

The purification procedure involves four simple steps: lyse, bind, wash, and elute, ensuring safe and reproducible handling of potentially infectious samples. With the option to choose from different elution volumes, users have the flexibility to tailor the protocol to their specific requirements, optimizing downstream applications such as amplification and detection reactions.

XTra™ DNA Kits for Automation are compatible with the Certal CHO Detection Kit and the Certal Vero Detection Kit, facilitating highly sensitive detection of residual genomic DNA from CHO and Vero cell lines using quantitative PCR. For precise and reliable results, the Rotor-Gene Q real-time PCR cycler is recommended.

In terms of applications, these kits find utility in a wide range of settings, from bioprocess purification in biotechnology-derived product manufacturing to vaccine production and quality control. Whether researchers are working with biopharmaceutical protein drugs or virus-propagating cell lines, XTra™ DNA Kits for Automation provide efficient and automated solutions for nucleic acid purification, enhancing productivity and accelerating scientific discoveries.