Cleaves bond between neutral amino acid (X) and glycine in sequence Pro-X-Gly-Pro, which is found with high frequency in collagen.
Ecose™ Collagenase, Type I, powder
Price range: $230.00 through $350.00
Purchase this item and get Product Description
Collagenase is a unique protease that specifically cleaves bonds between a neutral amino acid (X) and glycine in the Pro-X-Gly-Pro sequence, abundant in collagen. It effectively degrades triple-helical native collagen fibrils found in connective tissues like skin, tendon, blood vessels, and bone. Collagenase disaggregation is widely used for culturing human tumors, mouse kidneys, and brain tissues, among others, as it operates gently at physiological temperature and pH, without requiring mechanical agitation or special equipment. Ecose™ Collagenase, Type I, derived from Clostridium histolyticum, is provided as a lyophilized, non-sterile powder designed for research applications such as cell and tissue dissociation and organ perfusion. Compared to other preparations, it exhibits average collagenase, caseinase, clostripain, and tryptic activities, making it ideal for digesting fat, adrenal, and liver tissues. Its activity exceeds 125 units/mg and should be stored at 2°C to 8°C, protected from light.
Content And Storage
Storage conditions: 2°C to 8°C. Protect from light.
Shipping conditions: Room temperature
Shelf life: 24 months from date of manufacture
Form
Lyophilized
Sterility
Non-sterile
Manufacturing Quality
cGMP-compliant under the ISO 13485 standard
Product Type
Collagenase
Product Line
Ecose™
| Product Quantity | 500 mg, 1 g |
|---|
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