VersaKit™ FFPE DNA/RNA for Automation

The VersaKit™ FFPE DNA/RNA for Automation revolutionizes molecular biology research with its innovative features and cutting-edge technology. Designed for automated extraction of both DNA and RNA from formalin-fixed paraffin-embedded (FFPE) samples, this kit offers unparalleled convenience, efficiency, and reliability.

The technology of the VersaKit™ FFPE DNA/RNA for Automation enables the extraction of DNA and RNA from the same sample without the need to divide the specimen. This unique capability not only streamlines the workflow but also eliminates the need for sample splitting, reducing sample consumption and optimizing crosslink removal for both nucleic acids.

Performance-wise, the VersaKit™ FFPE DNA/RNA for Automation delivers exceptional results. Through its automated purification process utilizing magnetic-bead technology and prefilled cartridges, it ensures superior yields of DNA and RNA from FFPE samples compared to manual methods or those from other suppliers. The kit’s workflow, depicted in the figures provided, highlights its high degree of automation and the resulting DNA and RNA yields from various sample types.

A fundamental principle underlying the VersaKit™ FFPE DNA/RNA for Automation is its ability to reverse crosslinking caused by formalin exposure without requiring overnight proteinase K incubation. This facilitates efficient extraction of both DNA and RNA while preserving their integrity and improving library complexity.

The procedure with the VersaKit™ FFPE DNA/RNA for Automation is straightforward. It begins with solubilizing and incubating a single FFPE sample to release RNA into the supernatant while retaining DNA in the pellet. Subsequent steps involve crosslink removal, binding of nucleic acids to magnetic particles, removal of contaminants, and elution of DNA and RNA into separate tubes.

The applications of DNA and RNA purified using the VersaKit™ FFPE DNA/RNA for Automation are extensive, ranging from real-time PCR to next-generation sequencing and microarray analysis. The kit’s specifications, including its ability to process 1-24 samples per run, its compatibility with FFPE tissue samples, and its yield variability depending on sample type and fixation conditions, underscore its versatility and reliability.

In summary, the Versakit™ FFPE DNA/RNA for Automation offers researchers a powerful tool for unlocking the molecular insights hidden within FFPE samples, facilitating breakthroughs in various fields of molecular biology research and diagnostics.